Protein Info for Pf6N2E2_538 in Pseudomonas fluorescens FW300-N2E2
Annotation: Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K05559, multicomponent K+:H+ antiporter subunit A (inferred from 71% identity to aaa:Acav_1966)Predicted SEED Role
"Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A159ZU96 at UniProt or InterPro
Protein Sequence (974 amino acids)
>Pf6N2E2_538 Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B (Pseudomonas fluorescens FW300-N2E2) MSLIVLLLLPFIGSCVAALLPHNARNAESLLAGLVALAGTVQVALLYPQIADGGVIREHY TWLPSLGLDFVLRLDGFAWLFSLLVLGIGTLVSLYARYYMSPDDPVPRFFAFFLAFMGAM LGLVISGNLIQMVFFWELTSLFSFLLIGYWHHRADARRGAYMALMVTGAGGLCLLAGVML LGHVVGSYELDKVLAAGDLIRAHGLYPILLPLILIGALSKSAQFPFHFWLPHAMAAPTPV SAYLHSATMVKAGVFLLARLWPSLSGSEEWFYIVGGAGACTLLLGAYCAMFQNDLKGLLA YSTISHLGLITLLLGLNSPLAAVAAVFHILNHATFKASLFMAAGIIDHESGTRDIRKLSG LVRLIPFTATLAMVASAAMAGVPLLNGFLSKEMFFAETVFISATAWVELALPIIATIAGT FSVAYSLRFTVDVFFGPAATDLPHTPHEPPRWMRAPVELLVFTCLVVGIFPAQVVGSLLA AAALPVVGGTLPEYSLAIWHGLNAPMIMSLVAMSGGIVLYLLLRNQFRQGHIKHPPFIGR LSGKRLFERCLVLMMRQGRRLERLISTRRLQAQLFWLVLAAVLAGLIPMLHSTLVWGDRP KIPGSIVFVSLWLLAIACALGAAWQAKYHRLAALTMVSVCGLMTCVTFVWFSAPDLALTQ LVVEVVTTVLILLGLRWLPRRIEDVSPLPNSERRARIRRLRDLLLSSAVGGGMALLSYAM LTRQTPNDISSFYLSRALPEGGGSNVVNVMLVDFRGFDTLGEITVLVAVALAVFALLRRF RPPKESMQLPAQQRLLAPDVVTDLVNPRHASDTALGFMMVPSVLVRLLLPIALVVSFYLF MRGHNQPGGGFVAGLVMSVAFILQYMVAGTQWVEAQMSLRPLRWMGTGLLFATATGLGAM AVGYPFLTTHTWHFKLPLLGDLHVASALFFDIGVYAVVVGSTLLILTALAHQSVRAHKPG LQAKPVAPVKGATA