Protein Info for Pf6N2E2_4419 in Pseudomonas fluorescens FW300-N2E2

Annotation: Diaminopimelate decarboxylase (EC 4.1.1.20)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 TIGR01048: diaminopimelate decarboxylase" amino acids 8 to 410 (403 residues), 524.6 bits, see alignment E=6.8e-162 PF00278: Orn_DAP_Arg_deC" amino acids 31 to 368 (338 residues), 97.2 bits, see alignment E=8.6e-32 PF01168: Ala_racemase_N" amino acids 34 to 229 (196 residues), 27.8 bits, see alignment E=3e-10 PF02784: Orn_Arg_deC_N" amino acids 35 to 280 (246 residues), 255 bits, see alignment E=1e-79

Best Hits

Swiss-Prot: 99% identical to DCDA_PSEFL: Diaminopimelate decarboxylase (lysA) from Pseudomonas fluorescens

KEGG orthology group: K01586, diaminopimelate decarboxylase [EC: 4.1.1.20] (inferred from 99% identity to pba:PSEBR_a5484)

Predicted SEED Role

"Diaminopimelate decarboxylase (EC 4.1.1.20)" in subsystem Lysine Biosynthesis DAP Pathway (EC 4.1.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GT12 at UniProt or InterPro

Protein Sequence (415 amino acids)

>Pf6N2E2_4419 Diaminopimelate decarboxylase (EC 4.1.1.20) (Pseudomonas fluorescens FW300-N2E2)
MDAFNYRGGELFAEGVALSAIAERFGTPTYVYSRAHIEAQYRTFADALVGMPHLVCFAVK
ANSNLGVLNVLARLGAGFDIVSGGELERVLAAGGSADKIVFSGVGKTREDMRRALEVGVH
CFNIESTDELERLQVVAAELGVRAPVSLRVNPDVDAGTHPYISTGLKENKFGIAIADAED
VYVRAAQLPNLEVLGVDCHIGSQLTTLEPFIDALDRLLALVDRLGDCGIYLRHIDLGGGV
GVRYRDEEPPLVADYIKAVRERLDGRDLALMFEPGRYIVANAGVLLTQVEYLKHTEHKDF
AIVDAAMNDLIRPALYQAWMDVTAVRPRDTAARPYDIVGPICETGDFLAKGRELALEEGD
LLAVHSAGAYGFVMSSNYNTRGRCAEVLVDGDQAFEVRRRETVAELFAGESLLPE