Protein Info for Pf6N2E2_4156 in Pseudomonas fluorescens FW300-N2E2

Annotation: GGDEF domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 PF20975: DGCcoil" amino acids 4 to 508 (505 residues), 232.2 bits, see alignment E=1.1e-72 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 526 to 686 (161 residues), 168.9 bits, see alignment E=4e-54 PF00990: GGDEF" amino acids 528 to 684 (157 residues), 158.6 bits, see alignment E=1.1e-50

Best Hits

KEGG orthology group: None (inferred from 94% identity to pba:PSEBR_a45)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A161GTM7 at UniProt or InterPro

Protein Sequence (688 amino acids)

>Pf6N2E2_4156 GGDEF domain protein (Pseudomonas fluorescens FW300-N2E2)
MSDDAERWREKYLKSIEQQEKLERRWAARLDLLRRGLVRSTLAAEGTDRAVDQCMKEMRE
VVRTDDMDAGLAALLPRLEKAVLDSEQRRETRVEQTSAALTALVAQLQSLPLPKDVSRPL
KKFAKQLEDRAGQAREIPLLLSELSGLQGKALSALDAPVEPSRPGLLQRLFGGQGHEDAT
PQPHDPAQASVAPASEMALPVAVAPATAAESVAPAPAPAPAPQPSVAEQAPALETTPEPV
ALTAPQIEIAPVPAPAPAAEVVQPASESDDQATEPAPLPTPLAEVPPVVAPALENPDELM
PEEPAQALPAPSLPPAELDEPLEGADVADAQYALPDSPEPSYSSVAKHIEDTLLGLLGDL
TLPERHRPQAEAMCERLRNGLNWYELLPILDDLAVLMLAITDTGQHEFEAYLQRLNDRLE
SFQSSLQAASEDHAENLSASREMDTQIREQVDGLQSSVKDADDLEGLKQVLENHLEGLLG
TMDHHRQQRDQREQEVSARLKSLADRVALMEQDAQVVRENLEEQRQKALIDPLTGLPNRA
AWSERLEHEVAQWQQHGNSLLLAMLDLDHFKRINDNYGHLAGDRVLKLIASVLRKRLRSG
DFIARFGGEEFVLLVPNTSLAAGAKLAEALRLAIEGCPFHFKGEPVTVTVSIGLTAFKPG
EHSDLVLKRADQALYRAKSSGRNHVELG