Protein Info for Pf6N2E2_4076 in Pseudomonas fluorescens FW300-N2E2

Annotation: L-Proline/Glycine betaine transporter ProP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 28 to 53 (26 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details amino acids 99 to 119 (21 residues), see Phobius details amino acids 126 to 151 (26 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 198 to 217 (20 residues), see Phobius details amino acids 252 to 274 (23 residues), see Phobius details amino acids 291 to 311 (21 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 347 to 369 (23 residues), see Phobius details amino acids 381 to 402 (22 residues), see Phobius details amino acids 409 to 428 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 29 to 240 (212 residues), 76.6 bits, see alignment E=1.9e-25 PF07690: MFS_1" amino acids 69 to 392 (324 residues), 86.9 bits, see alignment E=1.3e-28

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a117)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A0V0 at UniProt or InterPro

Protein Sequence (432 amino acids)

>Pf6N2E2_4076 L-Proline/Glycine betaine transporter ProP (Pseudomonas fluorescens FW300-N2E2)
MTTAPSSTATPAQPARPLTRNDYKTLSLSALGGALEFYDFIIFVFFATVVGKLFFPAEMP
EWLRLMQTFGIFAAGYLARPLGGIVMAHFGDLLGRKKMFTLSIFMMAVPTLIMGLLPTYA
QIGMWAPILLLLMRVIQGAAIGGEVPGAWVFVSEHVPVRHIGYACGTLTCGLTAGILLGS
LVATAINSLYTPAEVADYAWRIPFLLGGVFGLFSVYLRRWLHETPVFAELQLRKALAEEV
PLRAVLRDHRGAIAISMLLTWLLSAGVIVVILMTPTVLQTVYHFSPTTALQANSLAIVCL
SFGCIGAGVLADRFGAGRVFVFGSGLLLITFWTFYHCLFDHPEWLFPLYALSGLLVGTIG
AVPYVMVNAFPAVVRFSGLSFSYNLAYAIFGGLTPMVVTLLLKESPMGPAYYVAAICGIG
IVVGGYLWKKGR