Protein Info for Pf6N2E2_3796 in Pseudomonas fluorescens FW300-N2E2

Annotation: L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR03414: choline ABC transporter, periplasmic binding protein" amino acids 23 to 313 (291 residues), 442.2 bits, see alignment E=4.2e-137 PF04069: OpuAC" amino acids 32 to 285 (254 residues), 193.3 bits, see alignment E=3.1e-61

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 98% identity to pba:PSEBR_a387)

Predicted SEED Role

"L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160A0E5 at UniProt or InterPro

Protein Sequence (315 amino acids)

>Pf6N2E2_3796 L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) (Pseudomonas fluorescens FW300-N2E2)
MKRLFKRCLSILCGTTLLSAGAMAAEPASCQTVRMGVVNWTDVIATSGMADVLLTGLGYD
SKQTSAVQQIIFAGIRDKRLDIFLGYWKPAMDKNIAPFLAANQVKVLDKPSLADAQATLA
VPDYVAAAGLKTFADIARFKDQLGGKIYGIEPGSGANTTIKTMIETNHFGLKDFKLIESG
EAGMLAAVQRAVNRKEFVVFVGWTPHPMNINMHITYLTGSEDVYGPNEGAATVSTVTAPD
YAQRCPNVNRLLENLTFTAAQESQLMVPIMERKTPQDVARQWLREHPEDLQRWLAGVMSF
DGKDGVAAVQASLKN