Protein Info for Pf6N2E2_2679 in Pseudomonas fluorescens FW300-N2E2

Annotation: sensory box histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 transmembrane" amino acids 9 to 27 (19 residues), see Phobius details amino acids 187 to 204 (18 residues), see Phobius details PF00512: HisKA" amino acids 234 to 298 (65 residues), 75 bits, see alignment E=6e-25 PF02518: HATPase_c" amino acids 347 to 459 (113 residues), 93.7 bits, see alignment E=1.5e-30 PF00072: Response_reg" amino acids 489 to 600 (112 residues), 74.9 bits, see alignment E=8.9e-25

Best Hits

KEGG orthology group: None (inferred from 95% identity to pba:PSEBR_a1408)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165ZAB6 at UniProt or InterPro

Protein Sequence (622 amino acids)

>Pf6N2E2_2679 sensory box histidine kinase/response regulator (Pseudomonas fluorescens FW300-N2E2)
MLKIKRQTWALFLAYLIGAGGYIYYLYVETQSVLTDNINNKLLHAALGASAILGDRYHDN
LVDKQSKSQAQDWDTIQRLSGFNESMGTAFVYSVIKRGAKAYLISSSASKEEIQEKNFVR
FFDPYPDASQALLDSFERTEPTWIDYSDHWGDFRAVFVPLKSQDGTVYVVGAEVTLADYY
QQLNHDSLYHIILAILVFLAFLLLRMRAHLQQLRVNEQVLNQAKNAAEDADRSKTSFLAT
MSHEIRTPMYGVIGATELLARSALDPEQRRLLTTIHSSGRTLLSLIDNILDLAKIEAGKL
ELKPRVFEVRALVSSCMELIRQNIQDKPIVLEAQFSPDVPPLVKTDMDCLRQVLINLLGN
AVKFTEAGKISLLVTTSGYGSQAWLDFSIRDTGIGIPTERQDNLFKPFVQFKGAASQRFT
GSGLGLSICKNLLEAQQGTLTFTSQPGLGSTFSFSLPLALFSVSEIPIKDDHAAVGFDSS
FAEDYPLDILLVENHPVSQKVAMAMLQELGYTPDLASDGLEAVNRCMASTPEIILMDINM
PVMDGMEAVRRIRELPQGDTCYIVAFTASVFSSEIERFRAGGADDVLTKPANFQALTRVL
QRAASHRHQRQATPWVVDELSS