Protein Info for Pf6N2E2_2677 in Pseudomonas fluorescens FW300-N2E2

Annotation: Small-conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 transmembrane" amino acids 24 to 47 (24 residues), see Phobius details amino acids 72 to 91 (20 residues), see Phobius details amino acids 100 to 126 (27 residues), see Phobius details amino acids 144 to 164 (21 residues), see Phobius details amino acids 170 to 186 (17 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 188 to 256 (69 residues), 56.6 bits, see alignment E=1.2e-19

Best Hits

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a1410)

Predicted SEED Role

"Small-conductance mechanosensitive channel"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A159ZW95 at UniProt or InterPro

Protein Sequence (432 amino acids)

>Pf6N2E2_2677 Small-conductance mechanosensitive channel (Pseudomonas fluorescens FW300-N2E2)
MDIKQLWVNLQDLWGALDQHPLLHSSLALMLLLVIALVLGRVARYLILHAAKLLGRQPAL
NWVNDLRQNKVFHRLAQMTPSLIIQFGLHLVPELSKTSLIFLGNVALAFTILFLVLALSA
LLSALLDVYARTEHARTRSIKGYVQLTKMVLYVFGAIIIVATLIDRSPLLLLSGLGAMSA
VILLVYKDTLLSFVASVQLTSNDMLRVGDWIEMPQVGADGDVVDITLHTVKVQNFDKTIV
SIPTWRLMSESFKNWRGMQQSGGRRIKRSLFIDASGVRFLHDEEEQRLTQVRLLTDYIGR
KQAELKAWNEAQGNVAAMSANRRRMTNLGTFRAYALAYLKSHAEIQPNMTCMVRQLQTTA
QGIPLEIYCFTRTTAWTDYERIQGDIFDYLLAVMPEFGLNLYQQPSGTDLRSGLLPAVLG
ASHLPEPQKQVV