Protein Info for Pf6N2E2_1086 in Pseudomonas fluorescens FW300-N2E2

Annotation: Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 782 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01804: Penicil_amidase" amino acids 36 to 761 (726 residues), 452.4 bits, see alignment E=2.2e-139

Best Hits

Swiss-Prot: 73% identical to PVDQ_PSEPF: Acyl-homoserine lactone acylase PvdQ (pvdQ) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: None (inferred from 97% identity to pba:PSEBR_a2993)

Predicted SEED Role

"Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching" in subsystem Siderophore Pyoverdine (EC 3.5.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.-

Use Curated BLAST to search for 3.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165YYR3 at UniProt or InterPro

Protein Sequence (782 amino acids)

>Pf6N2E2_1086 Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching (Pseudomonas fluorescens FW300-N2E2)
MSGQLSRIGLAGAFLGIALGLSPVVNAQDDGQQASAEIRRTRFGVPHIRAQDERGLGYGI
GYAYAQDNLCLLANELVTVNAQRSRYFGPERRTVEQRENRVSDLFFSWLNTPQAVSGFWQ
AQTPQVQQLVEGYVAGYNRALVERKAKGLPEQCASEWVRPITALDLVKLTRRLLVEGGVG
QFAEALAGAQPPQASALAGTPVTGFAAAATRQQRFALERGSNALAIGSERSFNGRGMLLA
NPHFPWLGGMRFYQMHLTIPGKLDVMGAALPGLPMINIGFSQHLAWTHTVDSSKHFTLYR
LQLDPKDPTRYLLDGKSVPMSQQTVAVDVKQPDGQVQTVTRVVYGSQFGPIVQWPGRLDW
DNRFAYSLRDANLENDRVLAQWYAMNKAVTLKDLQDAVHKIQGIPWVNTLAVDDQGQSLY
MNVSVVPNVDAEKLARCSDPRAGLRLIVLDGSRSECAWSIDSKAVQKGTYAADRLPQLLR
RDYVQNSNDSAWMVNPAQPLSGYSPLISQQGQPLGLRARFALDRMSQLAKSGPVKIEDLQ
RMVMDDQVYLADQVMPDLLGVCAGDLGADASALVEACASLKAWDRKAGLNSGLGFVHFQH
IMDRLQAVPDSWRVAFDPKDPQHTPRGLAIERPAVLKAVRDAMLASVETVKVAGLSKDSQ
WQDVQVASSGSRQTPIHGGPGELGIYNAIQSVPGADGKREVVSGTSYLQVVTFDGNGPQA
QGLLAFSLSSDPASPYSADQTQAFSQKQWSVLPFTEQQIKADPHYQALIIRERDETGRVA
TQ