Protein Info for Pf1N1B4_3529 in Pseudomonas fluorescens FW300-N1B4

Annotation: Membrane bound c-di-GMP receptor LapD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 151 to 170 (20 residues), see Phobius details PF16448: LapD_MoxY_N" amino acids 23 to 145 (123 residues), 137.9 bits, see alignment E=3.4e-44 PF00672: HAMP" amino acids 168 to 219 (52 residues), 31.9 bits, see alignment 2.7e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 234 to 391 (158 residues), 51.3 bits, see alignment E=5.3e-18 PF00990: GGDEF" amino acids 237 to 390 (154 residues), 71.8 bits, see alignment E=1.2e-23 PF00563: EAL" amino acids 415 to 643 (229 residues), 152.1 bits, see alignment E=3.4e-48

Best Hits

KEGG orthology group: None (inferred from 65% identity to pap:PSPA7_3896)

Predicted SEED Role

"Membrane bound c-di-GMP receptor LapD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A166PCQ0 at UniProt or InterPro

Protein Sequence (646 amino acids)

>Pf1N1B4_3529 Membrane bound c-di-GMP receptor LapD (Pseudomonas fluorescens FW300-N1B4)
MSLRKQLFLAICLFLLVAFSGSFFVSLESSREQVLSQLRSHAQDAATALGLSLTAQIDDP
AMIELMVSSIFDSGYFSSIRVIDIENEQVLVERSAPAQIEGVPQWFVSVVNLRPQGGDAL
ITRGWQQAARVEVLSNPQFALAKLWDSSLGSLIWLLICGLLSAVFGGWLLRRQLRPLDNM
VKQAEAISKREFRSLPKLPRTPELKRVVLAMNQMVEKLKALFAEEAARSENLRAESYQDA
LTGLANRRLLDEQLADQLLVSEQSRDGHLLMLRINDLIGLNQRLGGQRTDALIGAVGELL
KRLTQPPERRTWLAARNRGGEFSLLTPGLDNKDAARVASEISATLENLRLTGASDCMPVA
HLGVVAYHPGEPASEVLLRLDQALTQARQHPERPWVYQAHADTAPNHSQHDWRSWIDEAL
TEGKMQLYFQPVVQCADTSQVLHHKVLARLLDPQGEAIVAGHFLPWIERLGWSARFDLAM
LETTLEYLAANRWPLALSLSGSTLRDQAQLQQILDLLESLPELAPLLILEIDERQLPPPE
ELQRLSHSLLNTGYRIGLQHFGGSFSQIGNLTQLGLAYLKIDGAYIRGIDEQTDKRLFIE
AIFRATNSIDLPLIAEMVETQGELEVIRELGLFGVMGRLIGPPEPM