Protein Info for PFLU_RS22055 in Pseudomonas fluorescens SBW25-INTG

Annotation: AI-2E family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 7 to 40 (34 residues), see Phobius details amino acids 56 to 80 (25 residues), see Phobius details amino acids 149 to 169 (21 residues), see Phobius details amino acids 210 to 263 (54 residues), see Phobius details amino acids 269 to 295 (27 residues), see Phobius details amino acids 305 to 336 (32 residues), see Phobius details PF01594: AI-2E_transport" amino acids 13 to 338 (326 residues), 204.4 bits, see alignment E=1.3e-64

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU4497)

Predicted SEED Role

"Putative permease often clustered with de novo purine synthesis" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K100 at UniProt or InterPro

Protein Sequence (357 amino acids)

>PFLU_RS22055 AI-2E family transporter (Pseudomonas fluorescens SBW25-INTG)
MADTRRWVWLGGVVLLCVFVFLLHSILTPFLVALLLAYLFDPVVDRLEKAGLSRTWGVVA
VFALFTLIITALVLVLVPMLAKQLFRLYELAPQMLDWLQHTAMPWAQAKLGLADGFWKFD
KVKAAISEHMGQTTDIVGVILSQATASSLALIGWLTNLVLIPVVAFYLLRDWDIMMAKIR
SLLPRNREERIVSLAEECHEVLGAFVRGQLLVMLALGIIYAAGLMAIGLELGLLIGLIAG
LAAIVPYMGFVIGIGAALVAGLFQFGGDLYPMLGIVAVFMVGQALEGMVLTPLLVGDRIG
LHPVAVIFAILAGGELFGFTGILLALPVAAVIMVLVRHVHDLYKDSEVYTGVEDPDL