Protein Info for MPMX20_04460 in Enterobacter sp. TBS_079

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 TIGR00369: uncharacterized domain 1" amino acids 25 to 153 (129 residues), 50.4 bits, see alignment E=1.1e-17 PF13622: 4HBT_3" amino acids 52 to 153 (102 residues), 32.5 bits, see alignment E=8.2e-12 PF03061: 4HBT" amino acids 58 to 143 (86 residues), 48.9 bits, see alignment E=6.9e-17

Best Hits

Swiss-Prot: 95% identical to YIGI_SALTI: Uncharacterized protein YigI (yigI) from Salmonella typhi

KEGG orthology group: None (inferred from 93% identity to eok:G2583_4620)

MetaCyc: 93% identical to acyl-CoA thioesterase YigI (Escherichia coli K-12 substr. MG1655)
Acyl-CoA hydrolase. [EC: 3.1.2.20]; Palmitoyl-CoA hydrolase. [EC: 3.1.2.20, 3.1.2.2]; 3.1.2.2 [EC: 3.1.2.20, 3.1.2.2]

Predicted SEED Role

"putative protein PaaI, possibly involved in aromatic compounds catabolism"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.2.2 or 3.1.2.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>MPMX20_04460 hypothetical protein (Enterobacter sp. TBS_079)
MSAMLTAEEALKLVGEIFVYHMPFNRALGLELERYEKAFAQLSFNNQPMMVGNWAQSILH
GGVIASALDVAAGLVCVGSTLTRHDTINEDELRQRLSRMGTIDLRVDYLRPGRGNRFTAT
SSLLRAGNKVAVARVELHNEEQVYIASATATYMVG