Protein Info for MPMX20_03365 in Enterobacter sp. TBS_079

Annotation: Purine ribonucleoside efflux pump NepI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 25 to 43 (19 residues), see Phobius details amino acids 56 to 79 (24 residues), see Phobius details amino acids 91 to 109 (19 residues), see Phobius details amino acids 115 to 137 (23 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 179 to 197 (19 residues), see Phobius details amino acids 232 to 253 (22 residues), see Phobius details amino acids 260 to 279 (20 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 315 to 334 (20 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 378 to 400 (23 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 249 (220 residues), 91.6 bits, see alignment E=4.7e-30 amino acids 233 to 402 (170 residues), 47.7 bits, see alignment E=1.1e-16 PF00083: Sugar_tr" amino acids 59 to 193 (135 residues), 36.5 bits, see alignment E=2.8e-13

Best Hits

Swiss-Prot: 41% identical to YGAY_ECOLI: Putative uncharacterized transporter YgaY (ygaY) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 75% identity to bbr:BB2331)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>MPMX20_03365 Purine ribonucleoside efflux pump NepI (Enterobacter sp. TBS_079)
MSHASPLPSDRKTGHVRSGDMPRSLVWLFALASGLSVANVYYAQPLLDALSRDFGISHGA
IGGVVTATQIGCALALLFVVPLGDKVERRRLMALQLVVLVAALVTVGMAQTSTMLLAGML
ATGMAGTAMTQGLIAYAANAASPHEQGRVIGAAQGGVFMGLLVARVVSGGISDIAGWRGV
YLSAAGLMVIIAFPLWWRLPRLPAVPETMSYPRLIHSMLTLLREEKVLQVRGILALLMFA
AFNIFWSALVLPLSAPPYNLSHTAIGAFGLAGMAGALAATRAGEWADRGYARRTSAAALV
LLLLAWWPISLMDRSLGILLIGIVLLDLGGQALHVTNQSLIFRARPEAHSRLVGLYMLFY
AVGSGLGALSTTMTYAIAGWQGVCLTGAAVSLVALVFWWVTRKTG