Protein Info for MPMX20_03356 in Enterobacter sp. TBS_079

Annotation: Polyphosphate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 PF13089: PP_kinase_N" amino acids 7 to 109 (103 residues), 102.7 bits, see alignment E=3.4e-33 TIGR03705: polyphosphate kinase 1" amino acids 7 to 677 (671 residues), 850.8 bits, see alignment E=4e-260 PF02503: PP_kinase" amino acids 119 to 303 (185 residues), 156.5 bits, see alignment E=1.5e-49 PF17941: PP_kinase_C_1" amino acids 331 to 493 (163 residues), 248.2 bits, see alignment E=8e-78 PF13091: PLDc_2" amino acids 367 to 487 (121 residues), 39.3 bits, see alignment E=1.4e-13 PF13090: PP_kinase_C" amino acids 501 to 672 (172 residues), 228.6 bits, see alignment E=8.2e-72

Best Hits

Swiss-Prot: 98% identical to PPK1_KLEPN: Polyphosphate kinase (ppk) from Klebsiella pneumoniae

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 99% identity to enc:ECL_03793)

MetaCyc: 94% identical to polyphosphate kinase (Escherichia coli K-12 substr. MG1655)
Polyphosphate kinase. [EC: 2.7.4.1]

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>MPMX20_03356 Polyphosphate kinase (Enterobacter sp. TBS_079)
MGQEKLYIEKELSWLAFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRR
IIISEEQGLNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEMARNQIFLINERQLSVNQQ
TWLRHYFKHYLRQHITPILINRETDLVQFLKDDYTYLAVEIIRGDTIRYALLEIPSDKVP
RFVNLPPETPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVHEME
ASLMELMSSSLKQRLTAEPVRFVYQRDMPDAMVEMLRDKLTISRYDSIVPGGRYHNFKDF
IGFPNVGKANLVNKPLPRLRHLWFDKFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASF
DPNVLAIKINIYRVAKDSRIIDAMIHAAHNGKKVTVVVELQARFDEEANIHWARRLTEAG
VHVIFSAPGLKIHAKLFLISRKEGEDVVRYAHIGTGNFNEKTARIYTDYSLLTADARITN
EVRRVFNFIENPYRPVSFDYLLVSPQNSRRLLYDMIDKEIANAQKGLSSGITLKLNNLVD
KGLVDRLYAASSSGVPVNLLIRGMCSLIPELEGISDNIRVISIVDRYLEHDRVYIFDNAG
DKQVYLSSADWMTRNIDYRIEVATPLLDPRLKQQILDIIEILFSDTVKARYIDKELSNRY
VPRGNRRKVRSQLAIYDYIKSLEQPD