Protein Info for MPMX20_02965 in Enterobacter sp. TBS_079

Annotation: L-tartrate/succinate antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 519 transmembrane" amino acids 40 to 59 (20 residues), see Phobius details amino acids 65 to 82 (18 residues), see Phobius details amino acids 89 to 106 (18 residues), see Phobius details amino acids 126 to 149 (24 residues), see Phobius details amino acids 170 to 187 (18 residues), see Phobius details amino acids 225 to 254 (30 residues), see Phobius details amino acids 266 to 291 (26 residues), see Phobius details amino acids 320 to 339 (20 residues), see Phobius details amino acids 344 to 362 (19 residues), see Phobius details amino acids 373 to 396 (24 residues), see Phobius details amino acids 402 to 448 (47 residues), see Phobius details amino acids 455 to 473 (19 residues), see Phobius details amino acids 493 to 514 (22 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 39 to 518 (480 residues), 519.9 bits, see alignment E=7.6e-160 TIGR00785: transporter, divalent anion:Na+ symporter (DASS) family" amino acids 57 to 514 (458 residues), 488.2 bits, see alignment E=1.1e-150 PF03600: CitMHS" amino acids 78 to 447 (370 residues), 78.1 bits, see alignment E=7.1e-26

Best Hits

Swiss-Prot: 54% identical to TTDT_SHISS: L-tartrate/succinate antiporter (ttdT) from Shigella sonnei (strain Ss046)

KEGG orthology group: K11106, L-tartrate/succinate antiporter (inferred from 99% identity to enc:ECL_03251)

MetaCyc: 54% identical to L-tartrate:succinate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-127

Predicted SEED Role

"Citrate Succinate antiporter (TC 2.A.47.3.2)" (TC 2.A.47.3.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (519 amino acids)

>MPMX20_02965 L-tartrate/succinate antiporter (Enterobacter sp. TBS_079)
MNISAHNRIPDNLRRETMNTKTAVTPPGASHASNGKAKRLLMMALPVVVAVLLLFVPVPE
GLPPYAWHYFAIFVGVIVGLIFEPLPGAVIGLTGVVAIALCSQWVLFSPEQLADPKFKLA
GASFKWAVSGFGNSTVWLIFGAFMFAAGYDKTRFGRRLALILVKYLGRRSLTLGYAITFA
DLLLAPFTPSNTARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSM
FLSALAPNLLALALVKSTVGIDISWGTWFIAFLPLGVLLILTMPLLAYWFYPPEVKVNNE
VPLWATRELEKLGKLSRNEILLLIFVCCALLMWIFAAAWIEPAMAALLIVGLMLWTGVLE
WNDITGNKAAWNTFVWFATLVALADGLSSTGFISWLGKEGGLLMSGISPGVATIVLLLAF
YLLHYLFASTTAHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPI
YYGSGYLPTKDYWRLGTIFGAIFLAALLLIGYPWMSMMF