Protein Info for MPMX20_02282 in Enterobacter sp. TBS_079

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details PF00672: HAMP" amino acids 171 to 219 (49 residues), 25.1 bits, see alignment 2.8e-09 PF00512: HisKA" amino acids 225 to 279 (55 residues), 31.1 bits, see alignment 3e-11 PF02518: HATPase_c" amino acids 325 to 431 (107 residues), 81.7 bits, see alignment E=7.9e-27

Best Hits

KEGG orthology group: None (inferred from 86% identity to enc:ECL_01976)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>MPMX20_02282 Sensor histidine kinase RcsC (Enterobacter sp. TBS_079)
MTLWPRSLLSRLLVIVLAGLLLANTLSLTLVMVERMHSARTVMLGNLENDVATSVAILDR
LPAQERAAWLPRLERGNYRYILGPGEPGAPPEDKRSRDAIRTLKETLTADYPLTFTAVPG
PISHIQAHLTLRDGAPLTIDLTPRMPPVASWLPVVLVLQLLLLAACAWIAVRQVIRPFSQ
FTRAVDALDPAANTPMTEKGPVEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPI
TRMKLRVEMAEQPELRDKLLNDLDNMTRLVREGIAYARSSESLEETSLKLELNAWVNSIA
CDYQDIGKNVQFQANDARLPIVTRPQALRRVMTNLLDNALKFGGYAVIEIDDSSAGHIAI
HILDGGPGIPEAELDAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLDGKLRLANLPE
GGLKVTVTLPRR