Protein Info for MPMX20_01693 in Enterobacter sp. TBS_079

Annotation: Putative pyrimidine permease RutG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 60 to 77 (18 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 111 to 131 (21 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 173 to 190 (18 residues), see Phobius details amino acids 197 to 219 (23 residues), see Phobius details amino acids 244 to 264 (21 residues), see Phobius details amino acids 286 to 302 (17 residues), see Phobius details amino acids 319 to 338 (20 residues), see Phobius details amino acids 349 to 373 (25 residues), see Phobius details amino acids 385 to 425 (41 residues), see Phobius details TIGR03616: pyrimidine utilization transport protein G" amino acids 1 to 428 (428 residues), 823 bits, see alignment E=4.9e-252 TIGR00801: uracil-xanthine permease" amino acids 27 to 424 (398 residues), 383.5 bits, see alignment E=1.3e-118 PF00860: Xan_ur_permease" amino acids 32 to 401 (370 residues), 336.4 bits, see alignment E=1e-104

Best Hits

Swiss-Prot: 90% identical to RUTG_ECOLI: Putative pyrimidine permease RutG (rutG) from Escherichia coli (strain K12)

KEGG orthology group: K09016, putative pyrimidine permease RutG (inferred from 95% identity to enc:ECL_02628)

MetaCyc: 90% identical to pyrimidine:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN-132; TRANS-RXN-362

Predicted SEED Role

"Uracil permease" in subsystem De Novo Pyrimidine Synthesis or Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (442 amino acids)

>MPMX20_01693 Putative pyrimidine permease RutG (Enterobacter sp. TBS_079)
MAMFGFPHWQLKSTSTEPGVVAPDERLPLGPTLVMGVQHAVAMFGATVLMPMLMGLDPNL
SILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIATTGFNGQGINPNLSVALGGIIACG
LVYTLIGLVVMKIGTRWIERMMPPVVTGAVVMAIGLNLAPIAVRSVSGSPFESWMAVITV
LCIGLVAVFTRGMIQRLLILVGLIVACLVYALLANVFGLGKPVDFTLLHNAAWFGLPQVT
SPVFNTQAMMLIAPVAVILVAENLGHLKAVAGMTGRSMDPYMGRAFVGDGLATMLSGSVG
GSGVTTYAENIGVMAVTKVYSTLVFVAAAVMAMLLGFSPKFGALIHTIPAPVIGGASIVV
FGLIAVAGARIWVQHRVDLSQNSNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAIL
LNALLSRREAAAPQGDVVHQDS