Protein Info for MPMX20_01421 in Enterobacter sp. TBS_079

Annotation: putative multidrug ABC transporter permease YbhS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 182 to 205 (24 residues), see Phobius details amino acids 232 to 255 (24 residues), see Phobius details amino acids 261 to 283 (23 residues), see Phobius details amino acids 294 to 314 (21 residues), see Phobius details amino acids 340 to 342 (3 residues), see Phobius details amino acids 346 to 370 (25 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 13 to 341 (329 residues), 69.2 bits, see alignment E=5.7e-23 PF12698: ABC2_membrane_3" amino acids 29 to 370 (342 residues), 132.7 bits, see alignment E=2.7e-42 PF01061: ABC2_membrane" amino acids 171 to 341 (171 residues), 77.7 bits, see alignment E=1.4e-25

Best Hits

Swiss-Prot: 92% identical to YBHS_ECOLI: Probable multidrug ABC transporter permease YbhS (ybhS) from Escherichia coli (strain K12)

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 97% identity to enc:ECL_02942)

MetaCyc: 92% identical to ABC exporter membrane subunit YbhS (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-366 [EC: 7.6.2.2]

Predicted SEED Role

"ABC transport system, permease component YbhS"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (377 amino acids)

>MPMX20_01421 putative multidrug ABC transporter permease YbhS (Enterobacter sp. TBS_079)
MRNNAISWRRVRALCIKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILL
EQQSEEALDFTHTMTGSPYIDATISDNRQALIQMMQAGKIRGLVVIPVDFAANMARTDAS
APVQVITDGSEPNTANFVQGYVEGIWQLWQMQRAEDRGETFEPLIDVQTRYWFNPAAISQ
HFIIPGAVTIIMTVIGAILTSLVIAREWERGTMEALLSTEVTRVELLLCKLIPYYFLGML
AMLLCMLVSVFILGVPYRGSLVVLFFITSLFLLSTLGMGLLISTITRNQFNAAQVALNAA
FLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVSTLQSLFLAGNIPVVLIINTLFLLAS
ATMFIGLTWIKTKRRLD