Protein Info for MPMX20_01245 in Enterobacter sp. TBS_079

Annotation: Enterobactin exporter EntS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 52 to 75 (24 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 111 to 135 (25 residues), see Phobius details amino acids 147 to 170 (24 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details amino acids 217 to 242 (26 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 289 to 306 (18 residues), see Phobius details amino acids 312 to 336 (25 residues), see Phobius details amino acids 357 to 375 (19 residues), see Phobius details amino acids 382 to 401 (20 residues), see Phobius details PF05977: MFS_3" amino acids 16 to 405 (390 residues), 64.8 bits, see alignment E=5.5e-22 PF07690: MFS_1" amino acids 22 to 353 (332 residues), 92 bits, see alignment E=3.7e-30

Best Hits

Swiss-Prot: 84% identical to ENTS_SHIBS: Enterobactin exporter EntS (entS) from Shigella boydii serotype 4 (strain Sb227)

KEGG orthology group: K08225, MFS transporter, ENTS family, enterobactin (siderophore) exporter (inferred from 94% identity to enc:ECL_03110)

MetaCyc: 83% identical to enterobactin exporter EntS (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-496

Predicted SEED Role

"Enterobactin exporter EntS" in subsystem Siderophore Enterobactin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (415 amino acids)

>MPMX20_01245 Enterobactin exporter EntS (Enterobacter sp. TBS_079)
MNQKSWLLNLSLLKTHPAYRAVFIARFISILSLGLLGVAVPVQIQSMTHSSWLVGLSVTL
TGGAMFIGLMVGGVLADRYERKKLILLARGTCGVGFIGLCLNAMLPEPSLIAIYALGLWD
GFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMVGGLLLATGNVAWNYG
LAAAGTFITTLTLLRLPRLPPPPQPREHPLTSLMAAIRFLFSNPLIGGIALLGGLLTMAS
AVRVLYPALAGVWQMSASEIGVLYAAIPLGAACGALTSGNLAQSARPGLIMLLATLASFI
AIGFFSLMPVWALGVMCLVIFGWLSAISSLLQYTLIQTQTPEGMLGRINGLWTAQNVTGD
AIGAAILGGLGTIMTPVASASSSGFVLAMLGAILLVVLVELRRFRQEVVLNDSAA