Protein Info for MPMX20_00682 in Enterobacter sp. TBS_079

Annotation: Phosphopentomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01676: Metalloenzyme
  • amino acids 2 to 398 (397 residues), 189.2 bits, E=4.9e-60
• TIGR01696: phosphopentomutase
  • amino acids 3 to 405 (403 residues), 674.8 bits, E=1.6e-207

Best Hits

Swiss-Prot: 98% identical to DEOB_KLEP3: Phosphopentomutase (deoB) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K01839, phosphopentomutase [EC: 5.4.2.7] (inferred from 98% identity to kva:Kvar_4412)

MetaCyc: 95% identical to phosphopentomutase (Escherichia coli K-12 substr. MG1655)
Phosphopentomutase. [EC: 5.4.2.7]; 5.4.2.7 [EC: 5.4.2.7]

Predicted SEED Role

"Phosphopentomutase (EC 5.4.2.7)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 5.4.2.7)

MetaCyc Pathways

• superpathway of purine deoxyribonucleosides degradation (7/7 steps found)
• purine ribonucleosides degradation (6/6 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (6/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (3/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.7

Protein Sequence (407 amino acids)

>MPMX20_00682 Phosphopentomutase (Enterobacter sp. TBS_079)
MKRAFIMVLDSFGIGATEDAERFGDVGSDTMGHIAEACAKGEADNGRKGPLTLPNLTRLG
LVKAHEGSTGKIAAGMDGNAEVVGAYAWAHELSSGKDTPSGHWEIAGVPVLFDWGYFSDH
ENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDELGEEHMKTGKPIFYTSADSVFQIAC
HEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAP
TVLQKLVDEKDGHVVSVGKIADIYANCGITKKVKATGLDALFDATIKEMKEAGDKTIVFT
NFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMELVGEDDILILTADHGCDPTWTGTDHT
REHIPVLVYGPKVKPGSLGHRETFADIGQTIAKYFGTSDMEYGKAMF