Protein Info for MPMX20_00288 in Enterobacter sp. TBS_079

Annotation: Inner membrane protein YohK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 transmembrane" amino acids 6 to 21 (16 residues), see Phobius details amino acids 33 to 52 (20 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 148 to 169 (22 residues), see Phobius details amino acids 204 to 227 (24 residues), see Phobius details PF04172: LrgB" amino acids 14 to 225 (212 residues), 228.9 bits, see alignment E=2.3e-72

Best Hits

Swiss-Prot: 36% identical to YOHK_SHIFL: Inner membrane protein YohK (yohK) from Shigella flexneri

KEGG orthology group: None (inferred from 99% identity to enc:ECL_00327)

Predicted SEED Role

"CidA-associated membrane protein CidB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (229 amino acids)

>MPMX20_00288 Inner membrane protein YohK (Enterobacter sp. TBS_079)
MTNFQISVLCLIATLVIYFANKRLYRRFHALPLMPLVFTPILLVLMLVFGHISWQNYIGE
SHWLLWLLGPATIAFAVPVYDNLAIIKRHWMSLSAGVITATVVAVCSSVWLARLFTLPDE
IQRSLAVRSVTTPFALAAAKPLGGQPDLVALFVVVTGVFGMAVGDMLFLRLSIREGMAKG
AGFGAASHGAGTARSYELGQQEGVVASLVMMLSGVVMVLIAPLVAWVMF