Protein Info for MPMX20_00287 in Enterobacter sp. TBS_079

Annotation: Holin-like protein CidA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 136 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 74 to 95 (22 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details PF03788: LrgA" amino acids 31 to 122 (92 residues), 95 bits, see alignment E=1.1e-31

Best Hits

Swiss-Prot: 35% identical to CIDA_BACVZ: Holin-like protein CidA (cidA) from Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)

KEGG orthology group: K06518, holin-like protein (inferred from 93% identity to ent:Ent638_0272)

Predicted SEED Role

"Holin-like protein CidA" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (136 amino acids)

>MPMX20_00287 Holin-like protein CidA (Enterobacter sp. TBS_079)
MAMALSRVTPAVVQRLQVPVQVLLYAGLFVFAEYLVNWLHLPLPANLVGMVLMLTLILCR
VIPLNWVRAGARWLLAEMLLFFVPAVVAVVNYAQLLRVDGWRIFAVIALSTLMVLGATAW
VVDKVYRFEISRQKHD