Protein Info for MMP_RS07485 in Methanococcus maripaludis S2

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 71 to 89 (19 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 125 to 145 (21 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 197 to 219 (23 residues), see Phobius details PF10125: NADHdeh_related" amino acids 6 to 219 (214 residues), 306.4 bits, see alignment E=1e-95 PF00361: Proton_antipo_M" amino acids 90 to 184 (95 residues), 28.8 bits, see alignment E=7.4e-11

Best Hits

Swiss-Prot: 67% identical to Y522_METJA: Uncharacterized protein MJ0522 (MJ0522) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K14099, energy-converting hydrogenase A subunit H (inferred from 100% identity to mmp:MMP1455)

Predicted SEED Role

"Energy conserving hydrogenase Eha proton-sodium antiporter homolog protein H"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LX97 at UniProt or InterPro

Protein Sequence (220 amino acids)

>MMP_RS07485 membrane protein (Methanococcus maripaludis S2)
MLVEYIAGNFHGIIPLGDIVFYVTDFSLIAFIVAMVFTVIVYFTKPEKQLEAQVHEFGDK
FNYVTVEELKIRRFMSVVCGIATAFSMLTGDLFDFALFLAVIGISNIGIVAAVKKEWVLN
AAFHYGLITIVSSLPLFGAAALILGKTGTLSIFELAKNGNELFYQKLLYAVGMIGETGVA
PFYAAKAEMFRAPGAPYILMIHLSSLLVIVRTVEILLTIS