Protein Info for MMP_RS07325 in Methanococcus maripaludis S2

Annotation: glycosyl transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 signal peptide" amino acids 1 to 5 (5 residues), see Phobius details transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 53 to 80 (28 residues), see Phobius details amino acids 92 to 122 (31 residues), see Phobius details amino acids 131 to 153 (23 residues), see Phobius details amino acids 159 to 177 (19 residues), see Phobius details amino acids 195 to 219 (25 residues), see Phobius details amino acids 272 to 291 (20 residues), see Phobius details PF00953: Glycos_transf_4" amino acids 67 to 204 (138 residues), 91.6 bits, see alignment E=2.8e-30

Best Hits

KEGG orthology group: K01001, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC: 2.7.8.15] (inferred from 100% identity to mmp:MMP1423)

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.- or 2.7.8.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXC9 at UniProt or InterPro

Protein Sequence (299 amino acids)

>MMP_RS07325 glycosyl transferase (Methanococcus maripaludis S2)
MDLYFVLSALFCFVISLIFTKFMIKKMVNYKYGYDLHKADKIKVAEMGGLSPVVVSSVVM
LFFNPALSLSIFLPGFVGVIDDISRLNSKEKIVLTFLIGFPVAFFLKLGFLPSILLILGI
FVSSNLTNMLAGFNGLEIGMGILLCLFMAVVCLMNGDIFGFKVLILFLAAYLGLLYYNRY
PAKVFPGDTGTLPIGAFLATIAVWRGFIPELFILMIPFMVDALLKQFTAGVTKKDSVFTP
TQLKNGKLCVEGGYLSLPRMILMKKAMEEYKIVLVLWAIEAFFGILSILYTKYFGFNIF