Protein Info for MMP_RS07265 in Methanococcus maripaludis S2

Annotation: 50S ribosomal protein L5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 181 PF00281: Ribosomal_L5" amino acids 11 to 63 (53 residues), 69.4 bits, see alignment E=2.6e-23 PF00673: Ribosomal_L5_C" amino acids 67 to 167 (101 residues), 75.2 bits, see alignment E=3.7e-25

Best Hits

Swiss-Prot: 100% identical to RL5_METMP: 50S ribosomal protein L5 (rpl5) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K02931, large subunit ribosomal protein L5 (inferred from 100% identity to mmp:MMP1412)

Predicted SEED Role

"LSU ribosomal protein L11e (L5p)" in subsystem Ribosome LSU eukaryotic and archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXE0 at UniProt or InterPro

Protein Sequence (181 amino acids)

>MMP_RS07265 50S ribosomal protein L5 (Methanococcus maripaludis S2)
MSFQEVWEKEPMKKPRIQKVTVNFGVGEAGDRLTIGAKVIEELTGQSPVRTLAKQTNPAF
GIRKKLPIGLKVTLRGKKAEEFLKNAFTAFKACGKTLFASSFDQVGNFSFGVPEHIDFPG
QKYDPSVGIYGMDICVTFEKSGYRVKSRKVKRSHIPEKHLVTKDEAIEYIQAKFDTEVVR
E