Protein Info for MMP_RS07235 in Methanococcus maripaludis S2

Annotation: stress response translation initiation inhibitor YciH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 102 TIGR01158: putative translation initiation factor SUI1" amino acids 3 to 100 (98 residues), 116.7 bits, see alignment E=2.2e-38 PF01253: SUI1" amino acids 24 to 94 (71 residues), 78.9 bits, see alignment E=1.6e-26

Best Hits

Swiss-Prot: 100% identical to SUI1_METMP: Protein translation factor SUI1 homolog (MMP1406) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K03113, translation initiation factor 1 (inferred from 98% identity to mvn:Mevan_0717)

Predicted SEED Role

"Translation initiation factor SUI1-related protein" in subsystem Translation initiation factors eukaryotic and archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXE5 at UniProt or InterPro

Protein Sequence (102 amino acids)

>MMP_RS07235 stress response translation initiation inhibitor YciH (Methanococcus maripaludis S2)
MPEICPICGLPKDLCVCEEIAKEEQKIKVYVTKRRFGKLMTVVDGFDADLIDVKDLAKKL
KDICACGGTVKKDSIELQGDHRRKAEETLIKMGFSKDMIDVR