Protein Info for MMP_RS07220 in Methanococcus maripaludis S2

Annotation: 50S ribosomal protein L22

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 153 TIGR01038: ribosomal protein uL22" amino acids 9 to 151 (143 residues), 191.3 bits, see alignment E=4.5e-61 PF00237: Ribosomal_L22" amino acids 18 to 150 (133 residues), 92.4 bits, see alignment E=9.4e-31

Best Hits

Swiss-Prot: 100% identical to RL22_METMP: 50S ribosomal protein L22 (rpl22) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K02890, large subunit ribosomal protein L22 (inferred from 99% identity to mmq:MmarC5_0175)

Predicted SEED Role

"LSU ribosomal protein L17e (L22p)" in subsystem Ribosome LSU eukaryotic and archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P62649 at UniProt or InterPro

Protein Sequence (153 amino acids)

>MMP_RS07220 50S ribosomal protein L22 (Methanococcus maripaludis S2)
MAKLKYKVEADPKNTARAMGRTLRISRKHAIELCRELSGMKLDAAVAYLNRVIALETPVP
FKVHNKDLPHRKGKIGTHSGRFPQKASLEILNVLDNAKKNAEQKGLNTEKLRIKHISSNR
GFTIKRYMPRAFGRASPKNQETIHIQVILEEFY