Protein Info for MMP_RS07110 in Methanococcus maripaludis S2
Annotation: amidohydrolase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to Y699_METJA: Uncharacterized protein MJ0699 (MJ0699) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
KEGG orthology group: None (inferred from 100% identity to mmp:MMP1380)Predicted SEED Role
"Adenosine deaminase (EC 3.5.4.4), alternative form" (EC 3.5.4.4)
MetaCyc Pathways
- adenine and adenosine salvage V (2/3 steps found)
- purine deoxyribonucleosides degradation II (1/3 steps found)
- adenosine nucleotides degradation II (2/5 steps found)
- adenine and adenosine salvage III (1/4 steps found)
- purine deoxyribonucleosides degradation I (1/4 steps found)
- purine nucleotides degradation II (aerobic) (6/11 steps found)
- purine ribonucleosides degradation (2/6 steps found)
- superpathway of purine deoxyribonucleosides degradation (1/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.5.4.4
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6LXH1 at UniProt or InterPro
Protein Sequence (372 amino acids)
>MMP_RS07110 amidohydrolase family protein (Methanococcus maripaludis S2) MVYLNSNFLYGDDFEPKKGTLVIEDEIIKGFTSEHHSNVLNYKGLVIPPLINSHTHIGDN SIKDIGIGKSLDELVKPPNGLKHKFLNTCSEKELVQGMSEGLYDLENNGIKAFCDFRENG LNGINSLKSAFEDSNVSIKPIILGRPTQREENLLKDEISIILDNCDGLGLSGSNEYSDQE LKFICKLVNKKILSIHANEHKGSVQYSKEKYGISEIERLINLNIKPDFLIHATHSSSDDL SLLNENKIPVVVCPRANASFNVGLPDIPKMLEYNLKLGIGTDNFMANSPSIFKEMDFIYK IYHVDPKEILKMATINGAEILGLQNTGVIKEGYIPTFTFIKNGNILKTSKNIAASVVTRL ENGDVDSKFLVC