Protein Info for MMP_RS06995 in Methanococcus maripaludis S2

Annotation: TIGR00269 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 PF22082: TtuA_LIM_N" amino acids 2 to 27 (26 residues), 37.6 bits, see alignment (E = 3.7e-13) PF02540: NAD_synthase" amino acids 37 to 150 (114 residues), 28.6 bits, see alignment E=1.6e-10 PF03054: tRNA_Me_trans" amino acids 48 to 226 (179 residues), 39.2 bits, see alignment E=1.3e-13 PF01171: ATP_bind_3" amino acids 49 to 226 (178 residues), 47.9 bits, see alignment E=2.7e-16 TIGR00269: TIGR00269 family protein" amino acids 200 to 300 (101 residues), 99.2 bits, see alignment E=7.5e-33

Best Hits

Swiss-Prot: 49% identical to Y1157_METJA: Probable sulfurtransferase (MJ1157) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1356)

Predicted SEED Role

"n-type ATP pyrophosphatase superfamily / TilS and TtcA-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXJ4 at UniProt or InterPro

Protein Sequence (311 amino acids)

>MMP_RS06995 TIGR00269 family protein (Methanococcus maripaludis S2)
MKCRKCGKPSIYHQKHSGNNYCKECFIKETKRKVRKTLGRDVLKNNIKVAMGLSGGKDSL
VMAYLLNEYYKQIPNSNLIAIMVNEGIEGYRTDGIDAAVKFCEEYGIEYKIVHFKDYLGT
NLDEIVKIAKEKNLTMNPCSFCGVIRRKILNRVSIEEKCDFLAIGHNLDDVAQAVMMNYI
EGDVKKLAFLGKSLKHPKFVKRIKPLEKIPEDEVLLLAEMLELKYHKSPCPYSCLSFRSE
VSDITDNLEKNHPGSKYSIVRGYERLLEHIELPGYTGECKICGDLSATEVCKVCSYLKNL
GILEKSKFEKI