Protein Info for MMP_RS06095 in Methanococcus maripaludis S2

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 PF00005: ABC_tran" amino acids 18 to 164 (147 residues), 113.6 bits, see alignment E=1.1e-36

Best Hits

Swiss-Prot: 74% identical to Y089_METJA: Uncharacterized ABC transporter ATP-binding protein MJ0089 (MJ0089) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 100% identity to mmp:MMP1183)

Predicted SEED Role

"Iron(III) dicitrate transport ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.34

Use Curated BLAST to search for 3.6.3.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LY10 at UniProt or InterPro

Protein Sequence (253 amino acids)

>MMP_RS06095 ABC transporter ATP-binding protein (Methanococcus maripaludis S2)
MIVSVEGVEFKYKSTEILKDVKFEVEKGEVVSILGINGAGKSTLIKCINKILPPKKGTIT
VENLDVNKMDRLDLAKKVGYVPQRSNGNYMTVFDALLLGRKPHIKWEISKKDIEITENVL
KLLDLEKYALRNTNELSGGELQKVIIGRALVQEPKLILLDEPTNNLDLKNQLEVMRILKD
VSVSQNITSIIVMHDINLALRYSDKFLMLKDGKIFAEGGKEIINSQNIMEVYGVNTYVHN
LNGHLTIVPEEGY