Protein Info for MMP_RS06080 in Methanococcus maripaludis S2

Annotation: radical SAM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 PF04055: Radical_SAM" amino acids 64 to 218 (155 residues), 52.9 bits, see alignment E=7.6e-18 PF13353: Fer4_12" amino acids 66 to 169 (104 residues), 26.7 bits, see alignment E=9.6e-10 PF01497: Peripla_BP_2" amino acids 371 to 489 (119 residues), 29 bits, see alignment E=1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1180)

Predicted SEED Role

"hypothetical protein (multi-domain)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LY13 at UniProt or InterPro

Protein Sequence (585 amino acids)

>MMP_RS06080 radical SAM protein (Methanococcus maripaludis S2)
MKCTVCEIGCDISEGNYGRCNMYTNQNSKLIERFPNSYLTVLPITIETMPMVHFAPKNKF
LQVSTVGCNFNCQGCISETLTSNADALSGALTKASPTDIISRAKTEECRGIVFCLNDPAA
SYYTFLNLAKEAKKANLWVGCSTNGYFTETALKSLIPYLDFVNIGLKGSSNARYKECGAK
SAAPVFRNIRILHEAGVHVETSAMYINAGDEEILKAAEEVASVSKDIPLQVMRFVPFGEA
KPELEPTINKSEHIVDQLRSILNHVYLFNSPGTEYLTTKCPICGNEIIKREFYGPMGCRT
IESLDEGKCPCGWQVPLKGPINNEQFTEYGMLGGYRTTRAIEMAHAILFTLGIRDNEELG
DILGDIIKEDFIRGLHDRIQQIDSWLELIKDLAMRTGREKEGNELIAFIQERVDKINEGS
KLIKSCPTVYYSMGYPLFALNAERFETNLVEAAGGICVNKSLTRKGKPGVNISVNEINKL
SPEMMFISGFLSSPASDYVQYCKKHGIDNKAVRIGNICNVPTGWDFGSPRWILGFMFLAN
TIHPEIYSFDLENEQKEFYKRFYGIDVENVVTNRDFSRPAITTTK