Protein Info for MMP_RS06030 in Methanococcus maripaludis S2

Annotation: SufD family Fe-S cluster assembly protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF01458: SUFBD_core" amino acids 150 to 380 (231 residues), 171.2 bits, see alignment E=1.3e-54

Best Hits

Swiss-Prot: 53% identical to Y1150_METTH: UPF0051 protein MTH_1150 (MTH_1150) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

KEGG orthology group: K07033, (no description) (inferred from 100% identity to mmp:MMP1169)

Predicted SEED Role

"Iron-sulfur cluster assembly protein SufB" in subsystem Staphylococcal phi-Mu50B-like prophages

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LY24 at UniProt or InterPro

Protein Sequence (418 amino acids)

>MMP_RS06030 SufD family Fe-S cluster assembly protein (Methanococcus maripaludis S2)
MLSEKKLQQVREMAEKYKDVPAKFGEDIDLSMYPTPKENLLKVESLKDLNEDHKQALANV
GVDIEEKSTVGSYVQVNSDAIYSKMYSDIILMPITEALEKFELDDYYWNAVQMSDKYGAR
VAKELTEGYFIRAPKGVKKTIPLQTCLLIGSEEVSQNVHNIIIVEEGAELNVITGCTTSP
HVKSGLHLGVSEIYLEKNAKLTFTMIHNWGENVHVRPRTAIKMDDDSIFINNYVTMMPVK
SIQSYPTAYCEGKNAKATFQTIVYGKGSSNLDMGSRVILSGENSAADMISRVIVVDDAKV
ISRGHLIGAESNVKGHLECRGLILSNDGHILAVPELEAEKTDLELSHEAAVGKIAEDQIQ
YLMSRGLSEDEASSLIIKGFLSVDISGLPPELAKSVKEMMDDTRKCNVKSMFFTFLNI