Protein Info for MMP_RS05380 in Methanococcus maripaludis S2

Annotation: ATP synthase subunit K

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 60 to 76 (17 residues), see Phobius details amino acids 84 to 111 (28 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 156 to 184 (29 residues), see Phobius details amino acids 196 to 220 (25 residues), see Phobius details PF00137: ATP-synt_C" amino acids 12 to 71 (60 residues), 68.4 bits, see alignment E=2.5e-23 amino acids 84 to 142 (59 residues), 60.6 bits, see alignment E=6.9e-21 amino acids 158 to 216 (59 residues), 67.1 bits, see alignment E=6.6e-23

Best Hits

Swiss-Prot: 88% identical to ATPL_METJA: Probable ATPase proteolipid chain (MJ0221) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K02124, V-type H+-transporting ATPase subunit K [EC: 3.6.3.14] (inferred from 99% identity to mvn:Mevan_0363)

Predicted SEED Role

"V-type ATP synthase subunit K (EC 3.6.3.14)" in subsystem V-Type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYF1 at UniProt or InterPro

Protein Sequence (222 amino acids)

>MMP_RS05380 ATP synthase subunit K (Methanococcus maripaludis S2)
MVFENPLLLGAIGAGLAVGIAGLGSGIGAGITGASGAGVVAEDPNKFGTAIVFQALPQTQ
GLYGFLVAILILFVFKSAPEWAMLAAGIGTGLAGLSAIGQGIASAAGLGAVAEDDGIFGK
AMVFSVLPETQAIYGLLVAILLLVGVFASPGVTTIAALGAGLAVGFAGLSGIGQGITAAG
AIGATARDPDAMGKGLVLAVMPETFAIFGLLIAILIMLGIMF