Protein Info for MMP_RS04925 in Methanococcus maripaludis S2

Annotation: DUF530 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 PF04409: DUF530" amino acids 1 to 119 (119 residues), 145.8 bits, see alignment E=8.1e-47 amino acids 124 to 473 (350 residues), 313.8 bits, see alignment E=9.5e-98

Best Hits

Swiss-Prot: 49% identical to Y1110_METJA: Uncharacterized protein MJ1110 (MJ1110) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K09724, hypothetical protein (inferred from 100% identity to mmp:MMP0950)

Predicted SEED Role

"Uncharacterized protein MJ1110"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYP0 at UniProt or InterPro

Protein Sequence (476 amino acids)

>MMP_RS04925 DUF530 family protein (Methanococcus maripaludis S2)
MDSSVLIKECNDFLDCLSNFGKKLKDFDSKKEDSVNAVSETLENNLKILENFREKMELQG
FDTPYIGVGRLKGGEDDDIYEIINYSSYLRRMVDEKKGALERVKYAIVSHKIAIGNIQED
MGNKKILAHLSYDGSYKELLSKIPPFFIKSYKRILSVFETEGKGILSSITLSLVILENGK
RKFKRIKIEEEDYEGYIKKTFGDAIITSIKKNYSKNKLLNDQYVKKILSLAYLSACSDEI
IEKIDETLKETLSDEERCIVKKYRMICSDFKSSDCESGVIDVRAMEEIKLRKMNLKNDLE
DRGLYKNGKPLKKLKESLEMEDEILENISLEVPLKILSKDLLTYYLKKSADERTRSNQFP
SILVTPSPAHLNWLAVENIAPKKILDLKFLLEKELPKYEIPIKNLGGVSLYLLYDWNVVE
SFEFEKTEIEEILKLMAAINDVKELLKDKIDIKKFEKYSKIKKDKTKNFLNALGKL