Protein Info for MMP_RS04380 in Methanococcus maripaludis S2

Annotation: DUF4013 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 61 to 86 (26 residues), see Phobius details amino acids 112 to 136 (25 residues), see Phobius details amino acids 141 to 166 (26 residues), see Phobius details amino acids 188 to 216 (29 residues), see Phobius details amino acids 233 to 258 (26 residues), see Phobius details PF13197: DUF4013" amino acids 75 to 209 (135 residues), 58.7 bits, see alignment E=3.4e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0841)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYY8 at UniProt or InterPro

Protein Sequence (281 amino acids)

>MMP_RS04380 DUF4013 domain-containing protein (Methanococcus maripaludis S2)
MFFENYVFGPLKYGLSDLSKLLKGGIIYAVSIFLLIIGIFLAVYPYTGANLHIFGTATNS
LVFAVVALLSSVLGLGLLIVLNGYILKVIKLSLEKSVELPEWANYWDMLKNGVVFTLGIA
VIAVFGSILQNIITYIGNDGMVLIVLSMVIQLIISLYIPLSVVNFAQEDNFGAFFDIPKI
FKMMSFEYLGMFIVVSIISMLLMIIPMILVIFPLIGFFGMNMYTGPKMLFMASPLLLGVA
LFAFIVFSIVAVYVSFYSYRAYTNYFISKIPEKIGDFDQEL