Protein Info for MMP_RS04210 in Methanococcus maripaludis S2

Annotation: aldo/keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 PF00248: Aldo_ket_red" amino acids 16 to 267 (252 residues), 137.4 bits, see alignment E=1.4e-43 PF13187: Fer4_9" amino acids 295 to 364 (70 residues), 35.8 bits, see alignment E=1.7e-12

Best Hits

KEGG orthology group: K07079, (no description) (inferred from 100% identity to mmp:MMP0808)

Predicted SEED Role

"Aldo/keto reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZ21 at UniProt or InterPro

Protein Sequence (397 amino acids)

>MMP_RS04210 aldo/keto reductase (Methanococcus maripaludis S2)
MLYRTNPKNGDKLSILGFGAMRLPTKEDGSIDEEKATKMVRYAIDNGVNLVDTAWPYHMG
ECEPFLARALSEGYREKVKLSTKLPTWAVNTREDMDKFLNAQLEKLNTKQIDYYLLHTLT
KASWAKIKDLGVIDFLNSAKEDGRIKNAGFSYHGMQEDFAPIVDDYNWDFCLIQYNYLDE
KVQAGTKGLKYAASKGLGVFVMEPLRGGNLAGKTPEEVMEIWNKADKKRTTVEWALRWVW
NHPEVTSVLSGMTEPEQLEENIKIAEEGYPNSLTQKELGLIEQAALKYGELLKINCTGCG
YCMPCPANVDIPTCFGIYNNLHMFHDETQRFQYFATLSDIFWTNEPHFASQCTNCGICIE
KCPQYIQIPEMLEKVVAEFEGPDNDEKMAMVKSVFKM