Protein Info for MMP_RS04110 in Methanococcus maripaludis S2

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 732 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 298 to 316 (19 residues), see Phobius details PF14827: dCache_3" amino acids 43 to 288 (246 residues), 46.5 bits, see alignment E=1.1e-15 PF17201: Cache_3-Cache_2" amino acids 189 to 293 (105 residues), 64.5 bits, see alignment E=3.1e-21 PF17202: sCache_3_3" amino acids 191 to 292 (102 residues), 102.8 bits, see alignment E=3.9e-33 PF00672: HAMP" amino acids 318 to 366 (49 residues), 43.6 bits, see alignment 9e-15 PF00015: MCPsignal" amino acids 503 to 681 (179 residues), 106.9 bits, see alignment E=3.2e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0788)

Predicted SEED Role

"methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZ41 at UniProt or InterPro

Protein Sequence (732 amino acids)

>MMP_RS04110 methyl-accepting chemotaxis protein (Methanococcus maripaludis S2)
MKLINTKKLGTKMLIFSIISVLVPILVFGFVANDTIAGILDDNAQKSINTDIKIADQIIE
SRFIEFESICEYATNKADVITSVSNKDSEKLSIGVETFRAAINSDFVGVLDSNGNTIAST
AGPDIQIGSVAQKLITSGTKRSFEPISANTAYKINKNYKVENVDSALGMVVTYPIYENGN
VVGSIIIIDILNNNNEIVDQVKADTGDEATFSLGKQRISTSLIENGKRPVGTSISDEVWT
YVMSQNAVYKGTANVLGTELITAYAPLLDANDDVIGMVFVGAPQTDAIAAKNDARNKIIM
LALFGILIAFLITSYSNRKITKPIEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNK
MAENVKNLMKTMDMDKLELANLLNNVSDVMNRVAKGDFTARADESRENNKLEKAINTAVS
NVADLIKELREELDLLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSE
ELESTYENAKEVYSAAEETVKSSEEIKENSEIGVEKVENAISRMQSITNVIDELGKSIKM
LGEDGKKINEVTGLIKDIAEQTGLLALNASIEAARAGDAGKGFAVVASEIKALAEEIKKS
VEDINHTIDGVNSRIEDTVDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNESAIKINGI
KHGAQNASENTEGALKNAQDIAALSEEFTATAEEVTASTEELNSIIEEIRVIAEELTHVS
ERVSEKSNQFEI