Protein Info for MMP_RS03955 in Methanococcus maripaludis S2

Annotation: DUF3578 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 PF12102: MrcB_N" amino acids 11 to 190 (180 residues), 230.7 bits, see alignment E=1e-72 PF13020: NOV_C" amino acids 274 to 368 (95 residues), 87.6 bits, see alignment E=4.6e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0759)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZ70 at UniProt or InterPro

Protein Sequence (394 amino acids)

>MMP_RS03955 DUF3578 domain-containing protein (Methanococcus maripaludis S2)
LSGDLQTSILKILNEYTKESENSFKDNQLMKYVLRDIPEIFENKAALDSNKYKIKASVGQ
GNWAEIPWICIFDKEVTETAQKGYYIVYLFKNDMSGVYLSLNQGWTQYSEKYGSKGAKLN
IKKVSSVYKDILKSSSDFDFSEISLGKRTLAKGYELGHICGKYYSLSKFPEEKELINDLR
NLIGVYRELKGNVNSYIKNKGISEYYDVIEMLLAKYEKEDFDISEEDGEGGLTLEKSEIP
DKTEGFQNRNRTYSAVKTNFEHISKGSKKLGSSGEKLVYDYEVSFLNENGCPNLAKNVKH
VSEEDGDGAGYDILSYDLKGNEKYIEVKTTKNGKNTPFIVSRNELEFSKEYGDKYYIYRV
YEFNPKNKSGKFYVVNGPIDQEFNLEPKEYYVKR