Protein Info for MMP_RS03880 in Methanococcus maripaludis S2

Annotation: Fic family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 PF13784: Fic_N" amino acids 46 to 123 (78 residues), 70.4 bits, see alignment E=1.1e-23 PF02661: Fic" amino acids 127 to 232 (106 residues), 78.7 bits, see alignment E=4.9e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0742)

Predicted SEED Role

"Fic family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZ87 at UniProt or InterPro

Protein Sequence (389 amino acids)

>MMP_RS03880 Fic family protein (Methanococcus maripaludis S2)
MDPNDFKNLKTGKVIYDELNDYYHFEPCELPYEYIPNHKHLALSNDQALSNVSRLDGLLE
NFPNGELDLLERPFILKEAVLSSEIEGIHTTVSEVMISEKKKTKEKDTTLEVRNYKAALE
YGINKEITEELILEIHKILLNEVRGQDTTPGEYKRIQNYIGSKRTELKYAKFVPAAPKRT
KMLIRNLVEYINSPQEFPNLFKIAIIHYQFEVIHPFRDGNGRTGRILIILLLLKYNILKK
PVLYLSEFFNERRFEYQDRLYLVSSEGKIDDWIKFFLESVDIQSKRAFSFAKKLLDYKKN
LSNYIMDNDELKPNDKLKIIKIIDMLFRNAYIKIKDVESELEITYPTAKKLVDELVNLKI
IELEEMDKKRDKLYVSNKILEILDPKNIG