Protein Info for MMP_RS03730 in Methanococcus maripaludis S2

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00497: SBP_bac_3" amino acids 31 to 246 (216 residues), 82.7 bits, see alignment E=2.1e-27 PF09084: NMT1" amino acids 84 to 203 (120 residues), 21.2 bits, see alignment E=2.4e-08

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0712)

Predicted SEED Role

"Probable amino-acid ABC transporter precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZB7 at UniProt or InterPro

Protein Sequence (248 amino acids)

>MMP_RS03730 ABC transporter substrate-binding protein (Methanococcus maripaludis S2)
LKKATFILLFSILVITSACTDTKEYSESGTLTVGIYPYMPPYQYYENDKLEGFEIELVSE
IARRMNKQIEFVETDDKYGNYVAARSGTVDVSISAITKTASREKDSIYSELYMNSYSSLV
CVDSKYSRLADFEGKKIGIVDDTVYVDHAESYKKSVDFEIVKYYNYYDLNSALLDGEVDG
ALADYFTCKYFMKNDDDLTIIENTDIHYFGMVSSIGNEDLINNIDEVLMSMYNDGSYEKL
RLKYFEIE