Protein Info for MMP_RS03275 in Methanococcus maripaludis S2

Annotation: TIGR00266 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 TIGR00266: TIGR00266 family protein" amino acids 6 to 217 (212 residues), 242.8 bits, see alignment E=1.6e-76 PF01987: AIM24" amino acids 6 to 203 (198 residues), 214.8 bits, see alignment E=5.7e-68

Best Hits

Swiss-Prot: 33% identical to Y233_STRP6: Uncharacterized protein M6_Spy0233 (M6_Spy0233) from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0623)

Predicted SEED Role

"DUF124 domain-containing protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZK4 at UniProt or InterPro

Protein Sequence (222 amino acids)

>MMP_RS03275 TIGR00266 family protein (Methanococcus maripaludis S2)
MANYDFEITSRPSYSLLKINLKDQEIMTETGSMVYKDNGVNIETSAKGGVLGVLKRAVVG
ESIFMNKLSGSGRIALAPGYSGDIVHHELNGTLYASSGAYLASSSDLSIDTKFGGGKTFF
GGKGLFLMKIEGSGDVFLSSYGAVEEIELNNESIMVDNGNLVAFTGDLNYNLGKVGGLKS
TLLGGEGLVYNFSGTGKIYIQTRNIESFIDFITPYLPMPKQG