Protein Info for MMP_RS03105 in Methanococcus maripaludis S2

Annotation: radical SAM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 PF04055: Radical_SAM" amino acids 187 to 366 (180 residues), 31.7 bits, see alignment E=8.8e-12

Best Hits

Swiss-Prot: 72% identical to Y274_METJA: Uncharacterized protein MJ0274 (MJ0274) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0589)

Predicted SEED Role

"Uncharacterized protein MJ0274"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZN5 at UniProt or InterPro

Protein Sequence (510 amino acids)

>MMP_RS03105 radical SAM protein (Methanococcus maripaludis S2)
MKFLILDGYTDEPAGLGVPPYIGMYPRYAAGVLYKFKHDVDYITIDKLREELKKGYDFNR
YDVVIAICGFHTPGKYLNANPATLREFVSILYNFKGLKILGGPVATKFGSSLEGGKIKDE
SNLKYFFDVISEGDLDAVLHDLLKNNFKPEKTDGTRLRTYDELDEFARIGAKIVKLHPNY
PNIIAEIETYRGCTRAFSGGCSFCTEPRRYGSPKFRNSRDIIEEVRNLYENGIKYFRIGR
QPCMFSYMAKDVETTDVPVPNVLEIEKLFNGITSVSKPSVLHIDNANPSVIARHEKEGRE
IAKILVRHCTSGNVAAFGVESFDEKVISKNCLLTEPEDVLKAVNILNEIGGKRGENGMPY
LLPGINLLSGLKGESNDTFEINYDYLKEIYDSGNILRRINIRQVVPFFGTDITVKDVEKA
RKRKNLFLKFKEKIRTEIDNPMLKRMLPTETILKNVIVEVKEKNDLYFGRQFGSYPILIG
VAEKNVEIGKFVDIRVTGYGRRSITGKIVK