Protein Info for MMP_RS03005 in Methanococcus maripaludis S2

Annotation: S-layer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR01564: S-layer protein" amino acids 6 to 527 (522 residues), 314.2 bits, see alignment E=9.4e-98 PF05124: S_layer_C" amino acids 33 to 528 (496 residues), 206.5 bits, see alignment E=2.6e-65 PF05123: S_layer_N" amino acids 120 to 431 (312 residues), 204.8 bits, see alignment E=2.5e-64

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0569)

Predicted SEED Role

"S-layer protein precursor (Surface layer protein) (Cell surface glycoprotein) (Fragment)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZQ5 at UniProt or InterPro

Protein Sequence (528 amino acids)

>MMP_RS03005 S-layer protein (Methanococcus maripaludis S2)
MKSILKKIGCILVGSTVLSASITAAYALEKYGNINDFIDDDLIKNGNPDVYIVVGENAAA
LDVTSANKISAKIGTLTYSETIIEDESTVEYQIIGESESIDLLDGTDKLDSAGTEKSWIL
VTSADDDYADHFDDEEGNSFSYSGFSEADQTKSLGHLGYLLEVGDIDPENHFESDDDATE
IVFVRITDSNKNAGSQTFDIGKDMVYASIVYPNQVSAFKLTKDLKEGYEIPFLGKKYRIV
QIDEDDGIIYLGTASYDGTLEQGNYISSGEYQVVIGEILESGDEYSVEISILRNGNIIKE
HTEILRSDKSFSVIAGDLGVTVHDVWTNAAADTGYADITICRSLTELKLGEEYVNNWEVR
AVTNTGGTIDFLKTYEDNTVGIALVYSGSDIEEINDGDRIKIADYVNLVFDDEDDLDKMV
AEFKAERTVTTGSTGGTVISKSGEVPEIIMDSEIELDEADKNLILIGGPVANKLTKELQN
EGKIDIGNESPATASLIEGAANGNNVLVIAGGDRYSTESAVLSLINLI