Protein Info for MMP_RS02200 in Methanococcus maripaludis S2

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 296 to 314 (19 residues), see Phobius details PF14827: dCache_3" amino acids 43 to 281 (239 residues), 52.4 bits, see alignment E=1.5e-17 PF17202: sCache_3_3" amino acids 188 to 291 (104 residues), 111.6 bits, see alignment E=6.1e-36 PF17201: Cache_3-Cache_2" amino acids 189 to 292 (104 residues), 66.9 bits, see alignment E=4.7e-22 PF00672: HAMP" amino acids 315 to 364 (50 residues), 51.2 bits, see alignment 3.2e-17 PF00015: MCPsignal" amino acids 528 to 682 (155 residues), 108.2 bits, see alignment E=1.1e-34

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to mmp:MMP0413)

Predicted SEED Role

"methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M058 at UniProt or InterPro

Protein Sequence (731 amino acids)

>MMP_RS02200 methyl-accepting chemotaxis protein (Methanococcus maripaludis S2)
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDS
RFTELCTLAEYASYTQGVKTSIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSS
GEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTGTDSALSIVVAYPIYDDAGTL
GYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIA
LFGLLIAVVISLVSSRSITKPINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMA
KDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRADENRHKNKLQKTINHAIENV
SKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELG
EESKKINEVTVLIKDVAEQTGLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVE
DINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSAFMKIKESVETSAKMIAQIKD
NAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
LAEDADEFKTK