Protein Info for MMP_RS02150 in Methanococcus maripaludis S2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF13528: Glyco_trans_1_3" amino acids 1 to 319 (319 residues), 70.7 bits, see alignment E=2.6e-23 TIGR00661: conserved hypothetical protein" amino acids 2 to 318 (317 residues), 328.3 bits, see alignment E=2.6e-102 PF04101: Glyco_tran_28_C" amino acids 198 to 339 (142 residues), 86.6 bits, see alignment E=4.1e-28 PF06722: EryCIII-like_C" amino acids 254 to 345 (92 residues), 43.6 bits, see alignment E=6.2e-15 PF00201: UDPGT" amino acids 265 to 343 (79 residues), 22.7 bits, see alignment E=8.5e-09

Best Hits

Swiss-Prot: 58% identical to Y1255_METJA: Uncharacterized glycosyltransferase MJ1255 (MJ1255) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0403)

Predicted SEED Role

"Uncharacterized glycosyltransferase MM_1636 (EC 2.-.-.-)" (EC 2.-.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.-.-.-

Use Curated BLAST to search for 2.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M068 at UniProt or InterPro

Protein Sequence (361 amino acids)

>MMP_RS02150 hypothetical protein (Methanococcus maripaludis S2)
MKILISICGEGFGHTTRCIAIGNELSKKHEVKYAAYGKSKDFVEMSGGDVFETYPEIRLS
GKNGKFDVKKSIFNSDYHPARAIKKEMDIIKDYDPDLVISDCKYSSVVASKVLKKPYYII
TNQNCTKTDKKEKYIVYPVMEILNVINKSAEKVIIPDFPLPYTVCEYNLKLLENLSFIGP
LIRYDVVPEEISDEGYILCVIGGFEYRYKILELLNKISAKKGLKVKMVCGSYDVAEKLEK
IKSKNVEVIPLTTNMDELLKKCSFVVCHGGHSTLMEASCFGKPVITIPDLDHPEQENNAK
KISDMECGIALSYNTIDSNLEESIEKMVSTTKYYENSKKLMNLYLKNSGTDKVMDIVENG
L