Protein Info for MMP_RS02040 in Methanococcus maripaludis S2

Annotation: S-layer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR01564: S-layer protein" amino acids 6 to 575 (570 residues), 509.5 bits, see alignment E=6.2e-157 PF05124: S_layer_C" amino acids 34 to 575 (542 residues), 224.9 bits, see alignment E=5.5e-71 PF05123: S_layer_N" amino acids 116 to 484 (369 residues), 444 bits, see alignment E=4.9e-137

Best Hits

Swiss-Prot: 67% identical to CSG_METVS: S-layer protein (slmv1) from Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0383)

Predicted SEED Role

"S-layer protein precursor (Surface layer protein) (Cell surface glycoprotein) (Fragment)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M088 at UniProt or InterPro

Protein Sequence (575 amino acids)

>MMP_RS02040 S-layer protein (Methanococcus maripaludis S2)
MAMSMKKIGAIAVGGAMVASALATGAFAAEKVGDVDAFAADVVADGNANVDIVVGSNAAA
LDVVSAANVAAKIGSLMFKEGTVEDGSAQITVSASAESDEIKDLWATAPAAIAGQDKALV
ITAPDDDYTAVATGILGFADGVPAGTGLNLFGITTADAAVDLEDLQTLMIVEDADPSGWD
FYGTGNDFEAAEVLVAVVNTETTVPASTFGVGTPDLEVLEDEVVYASLAFVEDQYGNAAG
DYAALFPGMRIPLLGQEMVVVKLDTDDDLAIVGTEAYEGVIKQGDSYDVGNGYTVKIANV
LKQSGTAYKVDVQLLKDGKVVASKFDTVDKPAAPAAATQLKLVYKDMGIVVNAAWTDVGD
NYGYAELVIADNVVEMELGEEFIPDYEAYTVDLTAAGLTLSDKATAAGTIVGIALKYVGD
DVDKISKDKTFTIADYAKLDFDEDSGKIALKFLMDESKDVNINIGEKVSVLNAEIKLADI
EAEAKEAVVMTAPIAVLDSEASLDAADKGLILVGGPVVNALTAELADAGLVAIDNESPAT
LAVAAGAANGNDVLVVAGGDRAATEEAAEALIDML