Protein Info for MMP_RS01580 in Methanococcus maripaludis S2

Annotation: PQQ-binding-like beta-propeller repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 PF13570: PQQ_3" amino acids 10 to 47 (38 residues), 27.4 bits, see alignment 1.1e-09 amino acids 49 to 85 (37 residues), 18.6 bits, see alignment 6.3e-07 amino acids 87 to 124 (38 residues), 32.5 bits, see alignment 2.5e-11 amino acids 126 to 162 (37 residues), 26.9 bits, see alignment 1.5e-09 amino acids 164 to 202 (39 residues), 30.7 bits, see alignment 9.4e-11 amino acids 204 to 242 (39 residues), 41.8 bits, see alignment 3e-14 amino acids 244 to 280 (37 residues), 32.5 bits, see alignment 2.5e-11 PF01011: PQQ" amino acids 31 to 58 (28 residues), 22.6 bits, see alignment (E = 2e-08) amino acids 109 to 138 (30 residues), 29.9 bits, see alignment (E = 9.5e-11) amino acids 186 to 221 (36 residues), 35.3 bits, see alignment 1.9e-12 amino acids 226 to 261 (36 residues), 32.7 bits, see alignment 1.2e-11 PF13360: PQQ_2" amino acids 40 to 169 (130 residues), 51.1 bits, see alignment E=4.5e-17 amino acids 156 to 280 (125 residues), 49.4 bits, see alignment E=1.5e-16 PF16472: DUF5050" amino acids 63 to 248 (186 residues), 40.7 bits, see alignment E=5.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0294)

Predicted SEED Role

"Cell surface protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M0H6 at UniProt or InterPro

Protein Sequence (282 amino acids)

>MMP_RS01580 PQQ-binding-like beta-propeller repeat protein (Methanococcus maripaludis S2)
MLRGGVNDCKIKWEFLIGNSIDSSPILAKNGTIYLGSSNKNLYAINPDGSVKWFFKSGEI
IECKPSIGKDGTIYFGSDKVYAINPDGTEKWRFDTKKAIVSDFTIFEDILYVTSLDGHLY
AINPDGTEKWRFKTNDAITSAASIGKDGTIYFGSDKVYAINPDGTEKWNFYAGYWTVTRP
AISEDGTIYVTSLDGHLYAINPDGTEKWRFKTGKRIESSPVIGNTDTIYFGSYDGHLYAI
NPDGTEKWNFETGSWIIATPAIDENGTIYFGTRNGKFYALFN