Protein Info for MMP_RS01560 in Methanococcus maripaludis S2

Annotation: nascent polypeptide-associated complex protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 126 TIGR00264: alpha-NAC homolog" amino acids 1 to 124 (124 residues), 154.6 bits, see alignment E=6e-50 PF01849: NAC" amino acids 14 to 70 (57 residues), 52.7 bits, see alignment E=3.3e-18 PF19026: UBA_HYPK" amino acids 85 to 122 (38 residues), 38.1 bits, see alignment E=7.9e-14

Best Hits

Swiss-Prot: 100% identical to NAC_METMP: Nascent polypeptide-associated complex protein (nac) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K03626, nascent polypeptide-associated complex subunit alpha (inferred from 100% identity to mmp:MMP0290)

Predicted SEED Role

"Nascent polypeptide-associated complex protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M0I0 at UniProt or InterPro

Protein Sequence (126 amino acids)

>MMP_RS01560 nascent polypeptide-associated complex protein (Methanococcus maripaludis S2)
MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDKLLVFEKPKVQVMDMLGNK
TYSITGKAKKVAKEEEKIEDVEVKVEVTEEDIDMVSNQCGVSKEEAKKALEEVNGDLAEA
ILKLGN