Protein Info for MMP_RS00875 in Methanococcus maripaludis S2

Annotation: methanogenesis marker 3 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 TIGR03268: putative methanogenesis marker protein 3" amino acids 4 to 497 (494 residues), 559.6 bits, see alignment E=3.1e-172

Best Hits

Swiss-Prot: 60% identical to Y995_META3: UPF0288 protein Maeo_0995 (Maeo_0995) from Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0154)

Predicted SEED Role

"UPF0288 protein MJ1412"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M0W4 at UniProt or InterPro

Protein Sequence (501 amino acids)

>MMP_RS00875 methanogenesis marker 3 protein (Methanococcus maripaludis S2)
MNVLVNDKPKSGKTLKDVIKDEYYIPGSNIVIVKGTATVIKEETKKYMIKTTKGSFVVGI
TEENKSVDFWNKNYKSFEKKSLIWKSISDVSFGSIEINLPVSSLKQNFKKWDVVLSVSGL
DTSEGNLIFVQRDVTELYGLENPKIGILIGGKRVLKALTADDQIISIEKMRESKENIDYE
VTTDLDKEIQDDWKIYTYCKAELNGPSKSTEHALAILENGTLEISEHTNTYVADCRLQTL
LIDEENPENRDRGTITVRNVGNGVGKVYIYQENRASSLSHTVVGKVTDGIEIVDFSNSGQ
ITVKTSPERLNLIGKTQKDAKLLFEKHGITLKMEGNTDDDAVIVEQVPEYTMDILKSKEV
TTKGIEPEKLLYVEIFDKEAPTTAWYFRKTTGLTTKRIGTLKIYFKHDDISMFERNWDYS
KGLLPENTPKGSVDSEIIAVTNMAKRYKGYMGVRTSSHDKYGPTGETFEGTNIVGKVVKN
AEILKSVKQGENIYILEVNSN