Protein Info for MMP_RS00645 in Methanococcus maripaludis S2

Annotation: iron ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 538 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 66 to 89 (24 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 146 to 169 (24 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details amino acids 286 to 311 (26 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details amino acids 400 to 417 (18 residues), see Phobius details amino acids 464 to 487 (24 residues), see Phobius details amino acids 507 to 529 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 78 to 256 (179 residues), 34.5 bits, see alignment E=8.6e-13 amino acids 365 to 526 (162 residues), 42.7 bits, see alignment E=2.7e-15

Best Hits

KEGG orthology group: K02011, iron(III) transport system permease protein (inferred from 100% identity to mmp:MMP0109)

Predicted SEED Role

"Ferric iron ABC transporter, permease protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M109 at UniProt or InterPro

Protein Sequence (538 amino acids)

>MMP_RS00645 iron ABC transporter permease (Methanococcus maripaludis S2)
MKEVFNNEILKKIYPKILANVFLLIFIIYPVFTVFLQSFYGSNGFTLDAYSKFISDSYYF
GILKNSIVVACFSTIISIFLGFLFSIIIFKTDFKFKNFFKIAVFLPIITPGFISSLAYVF
LFGRHGAVTYGLLGLEPNIYGWKSVVIMQSIDYTTTAFFIISAVLLGISGEFEDAARNLG
SNEFQVFKKVTFPLLIPGILSAGLLIFMQSMADFGTPIIVGGNFNTLATASYFEIIGRYN
TQMASTLSVILLFPSMALFYLYSKYHKGYELKKSKITKYSLSNIQKVILGIPAVFFSIIA
YLLFFAVFVASFTKSFGHNYALTLDYFYEAISAGQLAIKNTLIYAMSSSILVAFLGVAYS
YIVYRGKFFGRKLMDLVITLPFAIPGTFMGLGYLLAFNNYPLLLTGTSSIIILNCMVRKL
PFSFKTGNSVLSQVEESVEEASLNLGASRLKTFYNVVLPLLKPAIIFSMIYTFIATIKSL
GSIIFLMTANTKVLSAMVFESTINRQLGVGACYSMFMVILSIIGILGILRLKGDKKWI