Protein Info for MMP_RS00240 in Methanococcus maripaludis S2

Annotation: type II secretion system F family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 60 to 78 (19 residues), see Phobius details amino acids 200 to 225 (26 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details PF00482: T2SSF" amino acids 93 to 217 (125 residues), 48.2 bits, see alignment E=5.3e-17

Best Hits

Swiss-Prot: 48% identical to Y779_METJA: Uncharacterized protein MJ0779 (MJ0779) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0038)

Predicted SEED Role

"Flp pilus assembly protein TadB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M179 at UniProt or InterPro

Protein Sequence (298 amino acids)

>MMP_RS00240 type II secretion system F family protein (Methanococcus maripaludis S2)
MDAKKYLDHIYHVLIVRNIKILKKTGRKLDERVFIGILLVITILPILLKIFLGFTLKTTL
ILTFVYLGSVLSLPTIMYESKMDKFDKNIPKALYVMVLSLDSGRSVVEAINEVIRSGIPE
VDVVFSKIVTLMTERKLSFEDAMILVSNSLDSKIFRQVGRLIIENRKYGGELADTLKKLA
KTLDDLQNLKSQLLSVTANGLAVGLIILCGVIPATAGLIGGYLTVISQLAPTMPSVEASQ
ISKAIETIQMGSGLFGLFFAVPLFGLKVNRMIITCAVCMTFAIGTFYAVLRLTGLLFA